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Alertness

Alertness is an aspect of wakefulness with hints of attention, and is the ability to interpret and maintain attention on different targets. Supplements that increase alertness tend to be anti-sleep or stimulatory agents.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect alertness
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Notable Very High See 2 studies
A decrease in alertness appears to occur alongside lemon balm ingestion (with or without sedation)
grade-c Minor - See study
An increase in the self-rated sensation of alertness is noted in older healthy adults supplementing with centella asiatica
grade-c Minor - See study
A decrease in alertness has been noted with melatonin supplementation
grade-c Minor - See study
An increase in alertness has been reported in persons using modafinil supplementation.
grade-c - - See study
grade-d Minor - See study
One small study noted a possible effect with 1,00 mg of an ashwagandha daily for 14 days.
grade-d Minor Very High See 2 studies
Increases in alertness tend to be during sleep deprivation or stress, rather than outright increases in alertness. Not overly potent