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Apolipoprotein B

Apolipoprotein B is the primary apolipoprotein (protein part of a lipoprotein) for LDL cholesterol, and increasing expression of apolipoprotein B is thought to help increase uptake of LDL from the blood into tissues.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect apolipoprotein b
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-b - Moderate See all 6 studies
Although at least one study has noted a decrease, usually there is no significant changes
grade-c Minor Very High See all 3 studies
There appear to be mild decreases of circulating Apolipoprotein B seen with supplementation of hesperidin in the populations with poor baseline cholesterol that actually see benefit from supplementation.
grade-c Minor - See study
A slight decrease in Apolipoprotein B has been noted with Pueraria Mirifica
grade-c Minor - See study
Apolipoprotein B may be abnormally elevated during zinc deficiency as it is reduced upon supplementation of zinc.
grade-c - - See study
grade-c - - See study
No known interactions with Apolipoprotein B.
grade-c - - See study
No significant influence on apolipoprotein B detected
grade-c - - See study
No significant alterations are observed in apolipoprotein B concentrations
grade-c - - See 2 studies
grade-c - Very High See all 4 studies
While a decrease in apolipoprotein B has been noted, most research suggests that it is not appreciably influenced.
grade-d Minor - See study
One preliminary study has noted a reduction in Apolipoprotein B concentrations with supplementation of a Formononetin rich red clover supplement.
grade-d Minor - See study
Somewhat of a decrease in hyperlipidemic patients consuming Mate tea
grade-d - Very High See 2 studies
No apparent effect in studies.
grade-d - - See study
No significant influence on Apolipoprotein B levels in serum
grade-d - - See study
No significant influence on Apolipoprotein B noted
grade-d - - See study
grade-d - - See study
No alterations in Apolipoprotein B have been noted
grade-d - - See study