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Cerebral Blood Flow

The amount of blood, and thus oxygen, that is delivered to the brain. Compounds can enhance cerebral blood flow by either fixing problems in unhealthy persons (fish oil) or outright increase flow (Resveratrol, Chocamine). Does not increase cognition per se, but may augment nootropics.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Feb 6, 2013
Last Updated:

Things To Know & Note

Also Known As

Neural Blood Flow

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect cerebral blood flow
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b
Minor
- See all 3 studies
Both increases and decreases seem to have been reported over the whole brain, and it seems that in people who do not experience orthostatic hypotension from marijuana it is generally an increase; blood flow to the ACC in particular is increased following THC, but this becomes a decrease during tolerance.
grade-c Minor - See study
Cerebral blood flow during cognitive testing in youth can be increased from 170mg cocoa flavanols, although may not coexist with increases in cognition.
grade-c Minor - See study
Appears to improve cerebral blood flow and volume in persons with low dietary fish intake
grade-c Minor Very High See all 3 studies
There appears to be a significant improvement in blood flow to the middle and anterior cerebral arteries, although other arteries are unaffected.
grade-c Minor - See study
A reduction in cerebral blood flow has been noted with green tea catechins; a simultaneous reduction in cognitive performance was not noted.
grade-c Minor - See study
In persons with senile dementia, supplementation of 360mg anapsos may increase blood flow in both hemispheres of the brain (720mg being less effective).
grade-c Minor - See study
500mg of resveratrol (high dose) has been confirmed to increase cerebral blood flow
grade-c - - See study
No significant influence on cerebral blood flow rates
grade-d Minor - See study
A decrease in cerebral blood flow has been noted to be independent of cognitive impairment