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Heart Rate

Heart Rate is a term used to refer to the amount of beats a heart gives in X amount of time, usually a minute. Heart rate is variable, and should be constant; arrythmia (irregular beats) are a cause for concern, and some supplements (usually stimulants) influence Heart Rate.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Feb 6, 2013
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect heart rate
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Minor High See all 6 studies
An increase in heart rate is noted, but not wholly consistent. It appears to affect those with lower caffeine tolerance or high overdoses of caffeine
grade-b Minor Moderate See all 5 studies
An increase in heart rate is present following ephedrine administration which correlates well with its psychostimulatory properties; this is not 100% reliable, and heart rate increases may not occur
grade-b Minor - See study
A small decrease in heart rate may occur following grape seed extract, although the studies are currently in persons with metabolic syndrome and not healthy persons
grade-b
Minor
- See all 10 studies
Similar to the diastolic blood pressure, heart rate modifications are subject to tolerance. New users may experience a reduced heart rate yet increased cardiac output, and heart rate during light exercise may be increased, with chronic users becoming tolerant to these effects.
grade-b - Very High See all 4 studies
No significant influence on heart rate seen with supplemental L-Arginine
grade-b - Very High See all 10 studies
Cocoa and the main constituent (-)-epicatechin do not appear to have an appreciable effect on heart rate at rest or during exercise when compared to placebo.
grade-b - Very High See all 4 studies
Heart rate during exercise, either submaximal or at lactate threshold, is not modified with dietary supplementation of colostrum.
grade-b - Very High See all 3 studies
No known influence on heart rate.
grade-b - Very High See all 6 studies
No significant influence of ginkgo biloba supplementation on heart rate.
grade-b - Very High See all 3 studies
Heart rate and pulse do not appear to be influenced from modafinil supplementation, despite a small increase in systolic blood pressure.
grade-b - High See all 3 studies
For the most part there is no significant effect, although one trial did note that after exercise during a recovery period ornithine had a higher heart rate. The reason for this is not known
grade-b - Very High See all 5 studies
There is no significant effect of sodium bicarbonate on heart rate at rest or during exercise
grade-c Minor - See study
A decrease has been noted in hypertensives alongside a reduction in blood pressure; no studies in otherwise healthy persons
grade-c Minor Moderate See 2 studies
Mixed influence on heart rate, a possible decrease secondary to weight loss and blood pressure reduction but no apparent alteration per se (possible increases with overdoses of green tea catechins)
grade-c Minor - See study
Both heart rate and pulse rate are increased with hoodia ingestion, which are thought to be related to toxic effects of the herb
grade-c Minor Moderate See 2 studies
A decrease in heart rate has been noted associated with supplementation
grade-c Minor Very High See 2 studies
A decrease in heart rate has been noted at rest over a long period of time (12 weeks in insomniacs) and acutely; both studies have used aromatherapy
grade-c Minor Very High See 2 studies
An increase in heart rate is present after nicotine ingestion due to the stimulatory properties
grade-c Minor - See study
May decrease heart rate alongside blood pressure in hyperlipidemics according to one trial
grade-c Minor - See study
A decrease in heart rate has been noted acutely in response to the aroma of clary sage
grade-c Minor - See study
A decrease in heart rate has been observed in hypertensive persons given tribulus supplementation
grade-c Minor Moderate See all 5 studies
A decrease in heart rate has been noted in exercising obese adults, a per se effect of Vitamin C on heart rate (rather than secondary to the rate of percieved exertion) seems unlikely.
grade-c Minor - See study
A decrease has been noted with Yerba Mate consumption, which is somewhat notable as stimulants tend to increase heart rate
grade-c Minor Very High See 2 studies
Due to stimulatory effects, an increase in heart rate follows yohimbine ingestion
grade-c - - See study
No significant effect on heart rate noted with DMAA supplementation despite the increase in blood pressure.
grade-c - Very High See 2 studies
No significant influence of alanylglutamine on heart rate during exercise relative to water
grade-c - - See study
No significant interaction between ALA and heart rate has been noted
grade-c - - See study
There is no significant influence on heart rate seen with 6-12mg anatabine in otherwise healthy persons
grade-c - - See study
grade-c - - See study
grade-c - Very High See 2 studies
No known interactions with heart rate and blueberry supplementation.
grade-c - Very High See 2 studies
No significant alterations in heart rate noted with BCAA supplementation at rest or during exercise
grade-c - - See 2 studies
grade-c - - See study
No significant influence on heart rate with acute ingestion of the herb in healthy persons.
grade-c - - See study
No significant influence on heart rate has been detected
grade-c - Very High See 2 studies
No significant influence on heart rate is known with chromium supplementation.
grade-c - Moderate See 2 studies
No significant influence on heart rate seems likely, although at least one study noted a random but significant reduction post-exercise
grade-c - - See study
No significant influence on heart rate seen with curcumin supplementation
grade-c - - See study
Heart rate at rest is not affected by ECA supplementation and may indirectly be lowered secondary to weight loss. However, an acute increase in heart rate is possible from the stimulatory effects of ephedrine
grade-c - - See study
grade-c - - See study
No significant acute effect on heart rate seen with fish oil supplementation
grade-c - - See study
No significant influences of Tyrosine on heart rate has been noted
grade-c - - See 2 studies
grade-c - - See study
No significant influence on heart rate noted with Maca ingestion
grade-c - Very High See 2 studies
No significant influence of melatonin on heart rate during waking either at rest or ambulation
grade-c - - See study
No significant influence on heart rate or pulse rate.
grade-c - Very High See all 3 studies
Does not appear to significantly influence heart rate
grade-c - - See study
No significant influence on heart rate
grade-c - Very High See 2 studies
No significant influence on heart rate with PS supplementation
grade-c - - See study
No significant alterations in heart rate noted
grade-c - - See study
No significant influence on heart rate either acutely or with prolonged supplementation.
grade-c - - See study
No significant influence on resting heart rate is seen with supplementation of red clover extract.
grade-c - Very High See 2 studies
No significant influences on heart rate found so far
grade-c - - See study
No significant alterations in heart rate are seen with Rooibos ingestion
grade-c - - See study
Three weeks Kanna usage does not appear to influence heart rate when compared to placebo.
grade-c - - See study
Despite the reduction in perceived stress, heart rate does not appear to be affected by supplemental soy lecithin
grade-c - Very High See 2 studies
No significant influence on heart rate detected with stevia consumption
grade-c - - See study
grade-c - Very High See all 3 studies
No significant influence on heart rate following Taurine supplementation
grade-c - - See 2 studies
grade-c - Very High See 2 studies
No significant influence on heart rate in subjects who are rehydrated and then subject to exercise.
grade-c - - See study
Heart rate during exercise in elite athletes is unaltered by supplementation of vitamin E.
grade-d Minor Moderate See 2 studies
A slight reduction in pulse rate has been noted in otherwise healthy but anxious persons in one study, but not another.
grade-d - - See study
No significant influence on heart rate when taken over the course of eight weeks.
grade-d - - See study
No significant interaction between heart rate and CLA supplementation
grade-d - - See study
No significant influences on heart rate are yet known
grade-d - High See all 4 studies
There is no inherent influence of garlic on heart rate, although when garlic aids cardiovascular performance in persons with heart problems it is associated with a reduced heart rate relative to control (due to less stress on the tissue).
grade-d - - See study
No significant alterations in heart rate associated with grapefruit ingestion
grade-d - - See study