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Interleukin 2

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jun 28, 2017
Last Updated:

Summary of Interleukin 2

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on Interleukin 2

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect interleukin 2
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-c Minor Moderate See 2 studies
Mixed effects on IL-2 concentrations, with an increase noted when supplemented around exercise and no change noted at rest.
grade-c Minor Very High See 2 studies
An increase in interleukin 2 (IL-2) concentrations has been noted in the elderly given supplementation of vitamin E alongside immunity enhancements.
grade-d Minor - See study
Interleukin 2 (IL-2) appears to be reduced during zinc deficiency, and this is normalized upon zinc sufficiency.
grade-d - - See study
grade-d - - See study
Possible large reduction due to 7 days of taking 1.5 g/d, however, pre-supplementation measurements weren't taken.