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Kidney Function

Kidney function tends to refer to a series of urinary or serum biomarkers that are thought to accurately assess kidney health, and supplements that change these biomarkers in a positive direction are thought to aid in kidney function.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:

Things To Know & Note

Also Known As

Renal function

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect kidney function
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-a - Very High See all 13 studies
In otherwise healthy persons given creatine supplementation, there is no significant beneficial nor negative influence on kidney function.
grade-c Minor Very High See 2 studies
Appears to promote kidney function in instances where function is normally hindered
grade-c - - See study
grade-c - - See study
Insufficient evidence to support enhanced kidney function.
grade-c - - See study
No apparent influence on kidney function (negative nor positive) with chromium supplementation in older sedentary adults.
grade-c - - See study
grade-c - - See 2 studies
grade-c - - See study
No significant alterations of kidney function in healthy persons given betaine (4g) for six months.
grade-c - Very High See 2 studies
Biomarkers of kidney function are not significantly altered with supplementation of vitamin E relative to placebo.
grade-d Notable - See study
Despite statistically weak evidence, case studies suggest curative effects. Potential of astragalus for aiding kidney function.
grade-d - - See study
No significant influence of CLA supplementation on renal functioning
grade-d - - See 2 studies
grade-d - - See study
No notable change in estimated glomerular filtration rate (eGFR) in type 2 diabetics over the course of 4 months.