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Quality of Life

Quality of life (QOL) refers to a general, all concompassing, response as to how tolerance and enjoyable one's living conditions are. QOL is impaired in various disease states that reduce functionality or cause pain, and treating these symptoms causes an increase in QOL.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:

Things To Know & Note

Also Known As


Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect quality of life
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-c Minor - See study
Minor effect in persons with cardiomyopathy, but it is unsure if berberine has a per se benefit on quality of life.
grade-c Minor Moderate See all 3 studies
An increase in QOL has been noted in persons who either have heart ailments or are at risk for them, but this may not be a universal increase (perhaps dependent on reducing disease state symptoms)
grade-c Minor - See study
The one study to measure subjective quality of life in persons with dementia found a significant improvement with supplementation
grade-c - - See study
Quality of life in cancer patients is unaffected despite an increase in NK cell activity, thought to be indicative of a therapeutic effect of supplementation.
grade-d Notable Moderate See 2 studies
grade-d Minor - See study
In one study in healthy, active adults, quality of life on the WHO-QOL scale was improved for physical function, psychological health, social relationships, and environmental factors.
grade-d - - See study
No apparent effect in one study in prostate cancer patients.