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Skin Quality

Skin quality tends to refer to an overall evaluation on (facial) skin parameters such as tightness, moisture content, and clearness from acne. Supplements that improve skin quality can be taken orally or topically as a cream.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect skin quality
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-b - - See all 3 studies
grade-c Minor - See study
Limited evidence supports its efficacy, difficult to assess potency due to no reference drug.
grade-c Minor - See study
Oral ingestion of high dose catechins (1400mg) has been shown to improve skin quality
grade-c Minor - See study
Oral supplementation of standard doses of procyanidins can improve skin quality in elderly women, other demographics not tested
grade-c Minor - See study
There appears to be an overall increase in skin texture and moisture content associated with oral supplementation of the isoflavones, and a depigmenting activity should also apply (not yet shown in humans)
grade-c Minor Very High See 2 studies
Overall skin quality appears to be increased with topical application of nicotinamide containing creams and lotions; mildly but beneficially influencing most measured parameters.
grade-c - - See study
grade-d Notable - See study
The lone study in women with oily skin noted that improvements in skin quality with a 2% orthosiphon cream were greater than the reference drug of 1% zinc gluconate on all parameters.
grade-d Minor - See study
May improve skin quality when topically applied
grade-d Minor - See study
Somewhat effective, not enough evidence to fully evaluate potency.
grade-d Minor - See study
Skin smoothness/roughness is beneficially influenced with topical application of ginkgo flavonoids at 0.3%
grade-d - - See study
No significant influence of topical hemp oil on skin quality